Antimicrobial peptide and Marine Biotechnology Lab
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- SpecialtyAntimicrobial peptides, Marine biotechnology
- E-mailzoocjy@gate.sinica.edu.tw
- Tel03-9880544 ext.15
- LabB103/MRS
1. Jan 2011~ now. Peptides (Impact factor: 2.843 (2019))
2. Nov 2010~Dec 2014.Molecular & Cellular Toxicology (Impact factor: 1.66 (2019))
3. April 2017~now.Genomics & Informatics Genomics & Informatics
4. July 9, 2020.Guest Editor for the open access journal Marine Drugs (ISSN 1660-3397). Special Issue ‘Marine Antimicrobial Peptide’ invited from MDPI Branch Office. (Impact factor: 4.073 (2020)) Special Issue "Advances in Marine Antimicrobial Peptides"
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2011, National Innovation Award (2011年第八屆國家新創獎)
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2011, The 4th SF Yang Bioagricultural Young Scientist Awardees (2011) (2011年楊祥發院士傑出農業科學年輕學者獎)
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2012, National Innovation Award (2012 年第九屆國家新創獎)
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2013, Taiwan Healthcare and Agricultural Biotech Industries Innovation and Excellence Awards (2013年,生醫暨生農產業選秀大賽,潛力新秀獎)
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2013, Bio Taipei Awards (2013台北生技獎,產學合作獎,銀獎,中央研究院細胞與個體生物學研究所臨海研究站 (中大型螢光觀賞魚之開發))
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2013年臺灣登豐獎,中央研究院細胞與個體生物學研究所臨海研究站 (中大型螢光觀賞魚之開發)
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2014, Taiwan Healthcare and Agricultural Biotech Industries Innovation and Excellence Awards (2014年,生醫暨生農產業選秀大賽,潛力新秀獎)
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2014年6月4日科技部主動召開新聞記者會介紹"中大型螢光觀賞魚之開發 "
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2019, National Innovation Award (2019 年第十六屆國家新創獎(魚類胜肽(pardaxin)在治療寵物腫瘤上之商品開發))
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2019年國家新創精進獎 (基因轉殖中型螢光觀賞魚之研發)
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2020 科技大觀園,《水族新寵 螢光魚》影片
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2020, National Innovation Award (2020年第17屆國家新創獎)
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Dec 2020 ~ Dec 2022, director in chief of Taiwan Marine Biotechnology Society (理事長,臺灣海洋生物技術學會)
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2021, National Innovation Award (2021 年第18屆國家新創獎 (抗菌胜肽在飼料添加物開發商品化之應用))
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Name | Job Title | Telephone | Remark | |
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Jyh-Yih Chen | Research Fellow | 03-9880544(15) | zoocjy@gate.sinica.edu.tw | |
Prakash Kishore Hazam | Postdoctoral Fellow | 03-9880544(23) | prakashkishor.hazam@gmail.com | |
Jih-Chao Yeh | Postdoctoral Fellow | 03-9880544(52) | jihchao@gmail.com | |
Wen-chun Lin | Research Assistant | 03-9880544(23) | hagirl19@gmail.com | |
Ming-Feng You | Research Assistant | 03-9880544(52) | b9611869@yahoo.com.tw | |
Abhishek Negi | Ph.D. student | 03-9880544(16) | abhisheknegi1995@yahoo.com | |
Sanjay Prasad Selvaraj | Ph.D. student | 03-9880544(52) | sanjayprazad18@gmail.com |
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WC Lin, Hsu KC, You MF, Lee KH*, Chi CH*, Chen JY*, 2023, “Octanoic acid promotes clearance of antibiotic-tolerant cells and eradicates biofilms of Staphylococcus aureus isolated from recurrent bovine mastitis”, Biofilm, (under review), *Corresponding Author.
Sanjay PS, Chen JY*, 2023, “Conjugation of antimicrobial peptides to enhance therapeutic efficacy”, Eur J Med Chem, (in press), *Corresponding Author.
Chu‐Yi Hsieh, Venugopal Rajanbabu, Chieh-Yu Pan*, Jyh-Yih Chen*, 2023, “Transcriptome analysis reveals modulation of differentially expressed genes in LPS-treated mouse macrophages (RAW264.7 cells) by grouper (Epinephelus coioides) Epinecidin-1”, Fish & Shellfish Immunology, (in press), *Corresponding Author.
Prakash Kishore Hazam‡, Chih-Cheng Cheng‡, Wen-Chun Lin, Chu-Yi Hsieh, Po-Hsien Hsu, Yun-Ru Chen, Chao-Chin Li, Po-Ren Hsueh, Jyh-Yih Chen*, 2023, “Strategic modification of low-activity natural antimicrobial peptides confers antibacterial potential in vitro and in vivo”, European Journal of Medicinal Chemistry, (in press), *Corresponding Author. ‡ These authors contributed equally as joint first authors.
Jih-Chao Yeh‡, Prakash Kishore Hazam‡, Chu-Yi Hsieh, Po-Hsien Hsu, Wen-Chun Lin, Yun-Ru Chen, Chao-Chin Li, Jyh-Yih Chen*, 2023, “Rational design of stapled antimicrobial peptides to enhance stability and in vivo potency against polymicrobial sepsis”, Microbiology Spectrum, (in press), *Corresponding Author. ‡ These authors contributed equally as joint first authors.
Chia-Wen Liu, Chu-Yi Hsieh, Jyh-Yih Chen*, 2022, “Investigations on the wound healing potential of tilapia piscidin (TP) 2-5 and TP2-6”, Marine drugs, *Corresponding Author.
Wen-Chun Lin, Yun-Ru Chen, Chi-Mu Chuang, Jyh-Yih Chen*, 2022, “A cationic amphipathic TP4 peptide-based antimicrobial formulation promotes eradication of bacterial vaginosis-associated bacterial biofilms”, Frontiers in Microbiology, *Corresponding Author.
Prakash Kishore Hazam, Chin-Cheng Cheng, Chu-Yi Hsieh, Wen-Chun Lin, Po-Hsien Hsu, Te-Li Chen, Yi-Tzu Lee, Jyh-Yih Chen*, 2022, “Development of bactericidal peptides against multi-drug-resistant Acinetobacter baumannii with enhanced stability and low toxicity”, International Journal of Molecular Sciences, 16;23(4):2191. *Corresponding Author.
Chia-Wen Liu, Bor-Chyuan Su, Jyh-Yih Chen*, 2021, “Tilapia piscidin 4 (TP4) reprograms M1 macrophages to M2 phenotypes in cell models of Gardnerella Vaginalis-induced vaginosis” Frontiers in Immunology, Dec 2;12:773013. *Corresponding Author.
Hsueh-Ming Tai, Ming-Feng You, Chia-Hua Lin, Tsung-Yu Tsai, Chieh-Yu Pan, Jyh-Yih Chen*, 2021, “Scale-up production of and dietary supplementation with the recombinant antimicrobial peptide tilapia piscidin 4 to improve growth performance in Gallus gallus domesticus”, PLoS One, Jun 24;16(6):e0253661. *Corresponding Author.
Pin-Yang Tu, Shin-Jie Huang, Venugopal Rajanbabu, Jen-Leih Wu, Jyh-Yih Chen*, 2021, “Comparative transcriptome analysis reveals ectopic delta-5 and delta-6 desaturases enhance protective gene expression upon Vibrio vulnificus challenge in Tilapia (Oreochromis niloticusis)”, BMC Genomics, Mar 22;22(1):200. *Corresponding Author.
Bor-Chyuan Su, Giun-Yi Hung, Yun-Chieh Tu, Wei-Chen Yeh, Meng-Chieh Lin, Jyh-Yih Chen*, 2021, “Marine antimicrobial peptide TP4 exerts anticancer effects on human synovial sarcoma cells via calcium overload, reactive oxygen species production and mitochondrial hyperpolarization”, Mar Drugs, Feb 5;19(2):93. *Corresponding Author.
Bor-Chyuan Su, Chen-Hung Ting, Kang-Yun Lee, Sheng-Ming Wu, Po-Hao Feng, Yao-Fei Chan, Jyh-Yih Chen*, 2021, “Novel PD-L1 mAb HC16 reveals upregulation of PD-L1 in BAC subtype and early-stage”, Histol Histopathol, Jan;36(1):77-89. *Corresponding Author.
Book
Venugopal Rajanbabu, Jyh-Yih Chen**, Jen-Leih Wu# (2015) Chapter 13. Antimicrobial peptides from marine organisms. In Handbook of Marine Biotechnology (ed., Kim, S.-K.), Springer. pp 747-758. ** Corresponding author. # Corresponding author.