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3D mitochondrial ultrastructure of Drosophila indirect flight muscle revealed by serial-section electron tomography

JoVE 2017/12/19

https://www.jove.com/video/56567

Mitochondria are cellular powerhouses that produce ATP, lipids and metabolites, as well as regulate calcium homeostasis and cell death. The unique cristae-rich double membrane ultrastructure of this organelle is elegantly arranged to carry out multiple functions by partitioning biomolecules. Mitochondrial ultrastructure is intimately linked with various functions; however the fine details of these structure-function relationships are only beginning to be described. Here we demonstrate the application of serial-section electron tomography to elucidate mitochondrial structure in Drosophila indirect flight muscle. Serial-section electron tomography may be adapted to study any cellular structure in three-dimensions.

 


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115台北市南港區研究院路二段128號
Tel: 02-27899515
Fax: 02-27858059
icob@gate.sinica.edu.tw
Copyright © ICOB 2013. All rights reserved. 最佳瀏覽網頁方式請用最新版IE11或其他瀏覽器 /瀏覽人數:1044538--
 瀏覽人數:1044538