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研究人員｜中央研究院 細胞與個體生物學研究所

研究人員
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側邊選單開關 研究人員
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文章內容區

  • 簡正鼎Cheng-Ting Chien
    特聘研究員Distinguished Research Fellow
友善列印
代表著作展開收合

Selected Publications

  1. Lin, C.-H., Li, H., Lee, Y.-N., Cheng, Y.-J., Wu, R.-M., and Chien, C.-T.* (2015) Lrrk regulates the dynamic profile of dendritic Golgi outposts through the golgin Lava lamp. J. Cell. Biol., 210(3) 471-483. [PDF]

  2. Huang, Y.-C., Lu, Y.-N., Wu, J.-T., Chien, C.-T.* and Pi, H.* (2014) The COP9 Signalosome Converts Temporal Hormone Signaling to Spatial Restriction on Neural Competence. PLoS Genet., 10(11):e1004760. [PDF]

  3. Tsai, P.-I., Wang, M., Kao, H.-H., Cheng, Y.-J., Lin, Y.-J., Chen, R.-H., and Chien, C.-T.* (2012) Activity-dependent retrograde Laminin A signaling regulates synapse growth at Drosophila neuromuscular junctions. Proc Natl Acad Sci USA., 109:17699-17704. [PDF]

  4. Yang, W.-K., Peng, Y.-H., Li, H., Lin, H.-C., Lin, Y.-J., Lai, T.-T., Suo, H., Wang, C.-H. Lin, W.-H., Ou, C.-Y., Zhou, X., Pi, H., Chang, H. C, Chien, C.-T.* (2011) Nak regulates localization of clathrin sites in higher-order dendrites to promote local dendrite growth. Neuron. 72(2) 285-299. [PDF]

  5. Wu, J.-T., Lin W.-H., Chen, W.-Yu., Huang, Y.-C., Tang, C.-Y., Ho, M. S., Pi, H., and Chien, C.-T., * (2011) CSN-mediated deneddylation differentially modulates Ci155 proteolysis to promote Hedgehog signalling responses. Nat. Commun., 2: 182. [PDF]

Publications List

  1. Lin, C.-H., Li, H., Lee, Y.-N., Cheng, Y.-J., Wu, R.-M., and Chien, C.-T.* (2015) Lrrk regulates the dynamic profile of dendritic Golgi outposts through the golgin Lava lamp. J. cell. Biol., 210(3) 471-483.

  2. Huang, Y.-C., Lu, Y.-N., Wu, J.-T., Chien, C.-T. * and Pi, H.-W. * (2014) The COP9 Signalosome Converts Temporal Hormone Signaling to Spatial Restriction on Neural Competence. PLoS Genet. 10(11):e1004760

  3. Wang, C.-H., Chen, G.-C., and Chien, C.-T.* (2014) The deubiquitinase Leon/USP5 regulates ubiquitin homeostasis during Drosophila development. Biochem. Biophys. Res. Commun. 452: 369-375

  4. Tsai, P.-I., Wang, M., Kao, H.-H., Chen, Y.-J., Lin, Y.-J., Chen, R.-H., and Chien, C.-T.* (2012) Activity-dependent retrograde Laminin A signaling regulates synapse growth at Drosophila neuromuscular junctions. Proc Natl Acad Sci USA., 109:17699-17704

  5. Tsai, P.-I., Wang, M., Kao, H.-H., Chen, Y.-J., Walker, J. A., Chen, R.-H., and Chien, C.-T.* (2012) Neurofibromin mediates FAK signaling in confining synapse growth at Drosophila neuromuscular junctions. J Neurosci., 32:16971-16981 

  6. Yang, W.-K., Peng, Y.-H., Li, H., Lin, H.-C., Lin, Y.-J., Lai, T.-T., Suo, H., Wang, C.-H. Lin, W.-H., Ou, C.-Y., Zhou, X., Pi, H., Chang, H. C, Chien, C.-T.* (2011) Nak regulates localization of clathrin sites in higher-order dendrites to promote local dendrite growth. Neuron. 72(2) 285-299.

  7. Lin, C.-H., Tsai, P.-I, Wu, R.-M. and Chien, C.-T.* (2011) LRRK2 Parkinson’s disease: from animal models to cellular mechanism. Rev. Neurosci., 22

  8. Lin, C.-H., Tsai, P.-I, Wu, R.-M., Chien, C.-T.* (2010) LRRK2 G2019S Mutation Induces Dendrite Degeneration through Mislocalization and Phosphorylation of Tau by Recruiting Autoactivated GSK3b., J Neurosci.,30(39):13138-13149

  9. Lin, H.-C., Wu, J.-T., Tan, B.-C., Chien, C.-T.* (2009) Cul4 and DDB1 regulate Orc2 localization, BrdU incorporation and Dup stability during gene amplification in Drosophila follicle cells. J Cell Sci., 122:2393-2401.

  10. Ho, M. S., Chen, H., Chen, M., Jacques, C., Giangrande, A.*, Chien, C.-T.* (2009) Gcm protein degradation suppresses proliferation of glial progenitors. Proc Natl Acad Sci USA., 106:6778-83.